Almost everyone at some point has taken ibuprofen to alleviate pain. I took it last 2 years ago. I had a nasty earache brought on by swimming in polluted seas. Not really being a medication kind of person I was, naively, blown away when it worked. I only took it sporadically for a week or so. It made me twitchy thinking about the potential side effects.

Ibuprofen is one of the most well-known Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), alongside others such as aspirin and naproxen. NSAIDs are estimated to be responsible for up to 30% of drug related admissions to hospitals. Here are some of the reasons why:

1. Gastrointestinal Issues: NSAIDs can irritate the lining of the stomach and intestines, leading to ulcers and bleeding. This risk is higher in people with a history of gastrointestinal problems or those taking high doses of NSAIDs over a long period. To mitigate this risk a Proton Pump Inhibitors (PPI) such as omeprazole may be prescribed. Proton Pump Inhibitors have been implicated in potential malabsorption of nutrients including vitamin B12, vitamin C, calcium, iron and magnesium. In addition, taken long term there are studies to suggest they may increase the risk of gastric cancers.

2. Cardiovascular Risks: Prolonged use of NSAIDs, especially at high doses, has been associated with an increased risk of heart attack, stroke, and other cardiovascular events. This risk may be higher in individuals with pre-existing heart conditions or those at risk of cardiovascular disease. NSAIDs can also affect the kidneys ability to regulate fluid and electrolytes leading to higher blood pressure and affecting some blood presssure mediaction such as ACE inhibitors and Beta Blockers.

3. Kidney Damage: NSAIDs can impair kidney function, particularly in susceptible individuals such as the elderly or those with pre-existing kidney disease. Long-term use may lead to chronic kidney disease or failure. Its rare but NSAIDs can also cause liver damage.

4. Asthma Exacerbation: NSAIDs can worsen asthma symptoms in some individuals, leading to increased frequency and severity of asthma attacks.

I’m in no way saying don’t take NSAIDs, but it’s important to be careful. Follow the recommended dosage and duration of treatment, and consult your GP if you have any concerns. Its also worth considering alternative pain management strategies.